Coming from an alchemist, as well as a guy who works with plenty of others, I would start off pointing out that if you attempt this at acolyte it won't be as awesome as your thinking. You will need help, because high levels of alchemy are not easy. Unless you have had a good 10+ threads of making small spawns then growing in size, you will likely get shot down.
Secondly, the pups themselves, before the transformation would just be NPCs and not require a submission. After though they will need species, unless there's only a few at which point it could be either way.
Lastly, if you would like help with your project I can definitely help. My character possesses original information from the Knotters of Entrails and has Palpatines Book on Alchemy. He has even gone into things like hardening bone so its like steel etc.